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CNIH2 Antibody

Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs) . Promotes their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates of activation, deactivation and desensitization. Blocks CACNG8-mediated resensitization of AMPA receptors. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25

UniProt

Q6PI25

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 31-59 from the human protein was used as the immunogen for the CNIH2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC-P, FACS, IF

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CNIH2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CNIH2 antibody is available for research use only.

Storage Conditions

Aliquot the CNIH2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CNIH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human brain tissue with CNIH2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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