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CPM Antibody / Carboxypeptidase M

The protein encoded by this gene is a membrane-bound arginine/lysine carboxypeptidase. Its expression is associated with monocyte to macrophage differentiation. This encoded protein contains hydrophobic regions at the amino and carboxy termini and has 6 potential asparagine-linked glycosylation sites. The active site residues of carboxypeptidases A and B are conserved in this protein. Three alternatively spliced transcript variants encoding the same protein have been described for this gene. [provided by RefSeq].

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

P14384

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 212-241 from the human protein was used as the immunogen for the CPM antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CPM antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CPM antibody is available for research use only.

Storage Conditions

Aliquot the CPM antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CPM antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human kidney tissue lysate with CPM antibody. Expected molecular weight: 51-65 kDa depending on glycosylation level.

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