IL-1 alpha, Human
IL-1 alpha is a ubiquitous and pivotal pro-inflammatory cytokine. IL-1 alpha is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha plays an important role in inflammation and bridges the innate and adaptive immune systems. IL-1 alpha mediates the activation of NF-kappa-B and the three MAPK pathways p38, p42/p44 and JNK pathways[1][4]. IL-1 alpha protein, Human is a recombinant protein consisting of 159 amino acids (S113-A271) and is produced by E. coli.
Product Specifications
Product Name Alternative
IL-1 alpha Protein, Human, Human, E. coli
UNSPSC
12352202
Type
Recombinant Proteins
Applications
COVID-19-immunoregulation
Assay Protocol
https://www.medchemexpress.com/cytokines/il-1-alpha-protein-human.html
Purity
98.0
Smiles
Molecular Formula
3552 (Gene_ID) P01583 (S113-A271) (Accession)
Molecular Weight
Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
References & Citations
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Storage Conditions
Stored at -20°C for 2 years
Scientific Category
Recombinant Proteins
Available Sizes
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