Tyrosyl-DNA phosphodiesterase 2 Antibody / TDP2 / ETS1 associated protein II

This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000

UniProt

O95551

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 246-272 from the human protein was used as the immunogen for the Tyrosyl-DNA phosphodiesterase 2 antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, IF, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Tyrosyl-DNA phosphodiesterase 2 antibody is available for research use only.

Storage Conditions

Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Tyrosyl-DNA phosphodiesterase 2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.