Tyrosyl-DNA phosphodiesterase 2 Antibody / TDP2 / ETS1 associated protein II
This gene encodes a member of a superfamily of divalent cation-dependent phosphodiesterases. The encoded protein associates with CD40, tumor necrosis factor (TNF) receptor-75 and TNF receptor associated factors (TRAFs), and inhibits nuclear factor-kappa-B activation. This protein has sequence and structural similarities with APE1 endonuclease, which is involved in both DNA repair and the activation of transcription factors.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
O95551
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 246-272 from the human protein was used as the immunogen for the Tyrosyl-DNA phosphodiesterase 2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IF, IHC-P, WB
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Tyrosyl-DNA phosphodiesterase 2 antibody is available for research use only.
Storage Conditions
Aliquot the Tyrosyl-DNA phosphodiesterase 2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Nuclear, cytoplasmic
Image Legend
Western blot testing of human A549 cell lysate with Tyrosyl-DNA phosphodiesterase 2 antibody. Expected molecular weight: 41-51 kDa.
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