Dipeptidyl peptidase 3 Antibody / DPP3

This gene encodes a protein that is a member of the M49 family of metallopeptidases. This cytoplasmic protein binds a single zinc ion with its zinc-binding motif (HELLGH) and has post-proline dipeptidyl aminopeptidase activity, cleaving Xaa-Pro dipeptides from the N-termini of proteins. Increased activity of this protein is associated with endometrial and ovarian cancers. Alternate transcriptional splice variants have been characterized.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:25, Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

Q9NY33

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 583-612 from the human protein was used as the immunogen for the Dipeptidyl peptidase 3 antibody.

Clonality

Polyclonal

Isotype

Applications

IF, FACS, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Dipeptidyl peptidase 3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Dipeptidyl peptidase 3 antibody is available for research use only.

Storage Conditions

Aliquot the Dipeptidyl peptidase 3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Dipeptidyl peptidase 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human uterus tissue with Dipeptidyl peptidase 3 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.