GPX3 Antibody

This gene product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

P22352

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 93-123 from the human protein was used as the immunogen for the GPX3 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the GPX3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This GPX3 antibody is available for research use only.

Storage Conditions

Aliquot the GPX3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the GPX3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, nuclear

Image Legend

Western blot testing of 1) human kidney, 2) human plasma, 3) mouse kidney, 4) mouse plasma and 5) rat kidney lysate with GPX3 antibody. Expected molecular weight: 23-26 kDa.