GAD2 Antibody / GAD65
This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Immunofluorescence: 1:25
UniProt
Q05329
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 109-138 from the human protein was used as the immunogen for the GAD2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, IF
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the GAD2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This GAD2 antibody is available for research use only.
Storage Conditions
Aliquot the GAD2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.nsjbio.com/tds-pdf/gad2-antibody-gad65-f54577
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human Jurkat cell lysate with GAD2 antibody. Predicted molecular weight ~65 kDa.
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
