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MEAK7 Antibody / TLDC1 / KIAA1609

Activates an alternative mTOR signaling through RPS6KB2 activation and EIF4EBP1 repression to regulate cell proliferation and migration. Recruits MTOR at the lysosome, essential for MTOR signaling at the lysosome. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

Q6P9B6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 426-456 from the human protein was used as the immunogen for the MEAK7 antibody .

Clonality

Polyclonal

Isotype

Ig

Applications

FACS, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MEAK7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MEAK7 antibody is available for research use only.

Storage Conditions

Aliquot the MEAK7 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the MEAK7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC testing of FFPE human uterus tissue with MEAK7 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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