DENND1B Antibody
Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.
Product Specifications
UniProt
Q6P3S1
Host
Rabbit
Immunogen
A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
FACS, IHC-P, WB
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This DENND1B antibody is available for research use only.
CAS Number
9007-83-4
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