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DENND1B Antibody

Clathrin-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 and bind to clathrin and clathrin adaptor protein-2. Thus, connecdenns link RAB35 activation with the clathrin machinery.

Product Specifications

UniProt

Q6P3S1

Host

Rabbit

Immunogen

A portion of amino acids 39-68 from the human protein was used as the immunogen for the DENND1B antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

FACS, IHC-P, WB

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the DENND1B antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This DENND1B antibody is available for research use only.

CAS Number

9007-83-4

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