BCL10 Antibody

Promotes apoptosis, pro-caspase-9 maturation and activation of NF-kappa-B via NIK and IKK. May be an adapter protein between upstream TNFR1-TRADD-RIP complex and the downstream NIK-IKK-IKAP complex. Is a substrate for MALT1.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000

UniProt

O95999

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the BCL10 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

1185CT13.2.1.2

Applications

IHC-P, FACS, WB

Purity

Protein G affinity

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the BCL10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This BCL10 antibody is available for research use only.

Storage Conditions

Aliquot the BCL10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the BCL10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Nuclear, cytoplasmic

Image Legend

IHC testing of FFPE human kidney tissue with BCL10 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.