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UGT2B4 Antibody

UDPGTs are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isozyme is active on polyhydroxylated estrogens (such as estriol, 4-hydroxyestrone and 2-hydroxyestriol) and xenobiotics (such as 4-methylumbelliferone, 1-naphthol, 4- nitrophenol, 2-aminophenol, 4-hydroxybiphenyl and menthol) . It is capable of 6 alpha-hydroxyglucuronidation of hyodeoxycholic acid.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000

UniProt

P06133

Host

Rabbit

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the UGT2B4 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the UGT2B4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This UGT2B4 antibody is available for research use only.

Storage Conditions

Aliquot the UGT2B4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the UGT2B4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) HepG2, 2) LNCaP and 3) MDA-MB-453 cell lysate with UGT2B4 antibody. Predicted molecular weight: 43/46/61 kDa (three isoforms) .

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