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VDAC2 Antibody

Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules. The channel adopts an open conformation at low or zero membrane potential and a closed conformation at potentials above 30-40 mV. The open state has a weak anion selectivity whereas the closed state is cation- selective.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000

UniProt

P45880

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human protein was used as the immunogen for the VDAC2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the VDAC2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This VDAC2 antibody is available for research use only.

Storage Conditions

Aliquot the VDAC2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the VDAC2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

IHC testing of FFPE human brain tissue with VDAC2 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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