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HTRA1 Antibody

HtrA1 is a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25

UniProt

Q92743

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 116-147 from the human protein was used as the immunogen for the HTRA1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF, IHC-P

Purity

Purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the HTRA1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This HTRA1 antibody is available for research use only.

Storage Conditions

Aliquot the HTRA1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the HtrA1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, cell membrane

Image Legend

Immunofluorescent staining of human HeLa cells with HTRA1 antibody (green) and DAPI nuclear stain (blue) .

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