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CD10 Antibody / Neprilysin / MME

Biologically important in the destruction of opioid peptides such as Met- and Leu-enkephalins by cleavage of a Gly-Phe bond. Able to cleave angiotensin-1, angiotensin-2 and angiotensin 1-9. Involved in the degradation of atrial natriuretic factor (ANF) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25

UniProt

P08473

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the CD10 antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

965CT9.1.1

Applications

WB, FACS, IHC-P

Purity

Protein G affinity

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CD10 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD10 antibody is available for research use only.

Storage Conditions

Aliquot the CD10 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC testing of FFPE human kidney tissue with CD10 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.

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