Density Regulated Protein Antibody / DENR
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Product Specifications
UniProt
O43583
Host
Mouse
Immunogen
Recombinant human protein was used as the immunogen for the Density Regulated Protein antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Applications
WB, IHC-P, FACS, IF
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Density Regulated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Density Regulated Protein antibody is available for research use only.
CAS Number
9007-83-4
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