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Density Regulated Protein Antibody / DENR

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.

Product Specifications

UniProt

O43583

Host

Mouse

Immunogen

Recombinant human protein was used as the immunogen for the Density Regulated Protein antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Applications

WB, IHC-P, FACS, IF

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Density Regulated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Density Regulated Protein antibody is available for research use only.

CAS Number

9007-83-4

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