Density Regulated Protein Antibody / DENR
May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitmnet of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits. Plays a role in the modulation of the translational profile of a subset of cancer-related mRNAs when recruited to the translational initiation complex by the oncogene MCTS1.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25
UniProt
O43583
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the Density Regulated Protein antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
1542CT106.51.79
Applications
WB, IHC-P, FACS, IF
Purity
Protein G affinity
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Density Regulated Protein antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Density Regulated Protein antibody is available for research use only.
Storage Conditions
Aliquot the Density Regulated Protein antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Frequently Asked Questions
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