DIO2 Antibody / Type II Iodothyronine Deiodinase

DIO2 belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3) .

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25

UniProt

Q92813

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 165-191 from the human protein was used as the immunogen for the DIO2 antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

WB, FACS, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the DIO2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This DIO2 antibody is available for research use only.

Storage Conditions

Aliquot the DIO2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the DIO2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.