PIGR Antibody

PIGR binds polymeric IgA and IgM at the basolateral surface of epithelial cells. The complex is then transported across the cell to be secreted at the apical surface. During this process a cleavage occurs that separates the extracellular (known as the secretory component) from the transmembrane segment.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:25 (1x10e6 cells), Immunofluorescence: 1:25, Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000

UniProt

P01833

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 646-672 from the human protein was used as the immunogen for the PIGR antibody.

Clonality

Polyclonal

Isotype

IgG

Applications

FACS, IF, IHC-P, WB

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PIGR antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PIGR antibody is available for research use only.

Storage Conditions

Aliquot the PIGR antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PIGR antibody may be required due to differences in protocols and secondary/substrate sensitivity.