MEK2 Antibody / MAP2K2

MAP2K2 is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. The inhibition or degradation of this kinase is found to be involved in the pathogenesis of Yersinia and anthrax.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

P36507

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 262-292 from the human protein was used as the immunogen for the MEK2 antibody.

Clonality

Polyclonal

Isotype

Applications

IF, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MEK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MEK2 antibody is available for research use only.

Storage Conditions

Aliquot the MEK2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the MEK2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.