PIM2 Antibody
Pim proteins (Pim-1, Pim-2 and Pim-3) are oncogene-encoded serine/threonine kinases. Pim-2 is highly homologous to Pim-1 with similar oncogenic functions. Pim-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of Pim-2 has also been observed in certain cancers.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000
UniProt
Q9P1W9
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 277-308 from the human protein was used as the immunogen for the PIM2 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB
Purity
SAS precipitation
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PIM2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PIM2 antibody is available for research use only.
Storage Conditions
Aliquot the PIM2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Western blot testing of human 1) K562 and 2) SW620 cell lysate with PIM2 antibody. Predicted molecular weight ~34 kDa.
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