TEC Antibody

TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

P42680

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 175-205 from the human protein was used as the immunogen for the TEC antibody.

Clonality

Polyclonal

Isotype

Applications

IF, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the TEC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TEC antibody is available for research use only.

Storage Conditions

Aliquot the TEC antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the TEC antibody may be required due to differences in protocols and secondary/substrate sensitivity.