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IFNGR2 Antibody

IFNGR2 is the non-ligand-binding beta chain of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25

UniProt

P38484

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 308-337 from the human protein was used as the immunogen for the IFNGR2 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, FACS, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the IFNGR2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IFNGR2 antibody is available for research use only.

Storage Conditions

Aliquot the IFNGR2 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the IFNGR2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic

Image Legend

Western blot testing of human skeletal muscle lysate with IFNGR2 antibody. Expected molecular weight: 37-55 kDa.

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