Cystathionine Beta Synthase Antibody / CBS

CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunofluorescence: 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25

UniProt

P35520

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 104-133 from the human protein was used as the immunogen for the Cystathionine Beta Synthase antibody.

Clonality

Polyclonal

Isotype

Applications

IF, WB, FACS, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Cystathionine Beta Synthase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Cystathionine Beta Synthase antibody is available for research use only.

Storage Conditions

Aliquot the Cystathionine Beta Synthase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Cystathionine Beta Synthase antibody may be required due to differences in protocols and secondary/substrate sensitivity.