COL6A1 Antibody / Collagen VI
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1 (VI), alpha2 (VI), and alpha3 (VI) chains. The protein COL6A1 is the alpha 1 subunit of type VI collagen (alpha1 (VI) chain) . Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunofluorescence: 1:25, Flow cytometry: 1:25 (1x10e6 cells), Immunohistochemistry (FFPE) : 1:25
UniProt
P12109
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 831-858 from the human protein was used as the immunogen for the COL6A1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IF, FACS, IHC-P
Purity
SAS precipitation
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the COL6A1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This COL6A1 antibody is available for research use only.
Storage Conditions
Aliquot the COL6A1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Frequently Asked Questions
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