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CD82 Antibody

The ST6 metastasis suppressor gene product is a membrane glycoprotein that is a member of the transmembrane 4 superfamily. Expression has been shown to be downregulated in tumor progression of human cancers and can be activated by p53 through a consensus binding sequence in the promoter. Its expression and that of p53 are strongly correlated, and the loss of expression of these two proteins is associated with poor survival for prostate cancer patients.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000

UniProt

P27701

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 239-267 from the human protein was used as the immunogen for the CD82 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

IHC-P, FACS, WB

Purity

SAS precipitation

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the CD82 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This CD82 antibody is available for research use only.

Storage Conditions

Aliquot the CD82 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the CD82 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human Jurkat cell lysate with CD82 antibody. Expected molecular weight: 30-60 kDa depending on glycosylation level.

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