Adrenomedullin antibody / ADM
ADM, a hypotensive peptide found in human pheochromocytoma, consists of 52 amino acids, has 1 intramolecular disulfide bond, and shows a slight homology with the calcitonin gene-related peptide. It may function as a hormone in circulation control because it is found in blood in a considerable concentration. The precursor, called preproadrenomedullin, is 185 amino acids long. By RNA-blot analysis, human adrenomedullin mRNA was found to be highly expressed in several tissues. Genomic ADM DNA consists of 4 exons and 3 introns, with the 5-prime flanking region containing TATA, CAAT, and GC boxes.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P35318
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 69-96 from the human protein was used as the immunogen for the Adrenomedullin antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Adrenomedullin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Adrenomedullin antibody is available for research use only.
Storage Conditions
Aliquot the Adrenomedullin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
Western blot testing of human MCF7 cell lysate with Adrenomedullin antibody.
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