TOX-3 Antibody

TOX-3 contains an HMG-box, indicating that it may be involved in bending and unwinding of DNA and alteration of chromatin structure. The C-terminus of the encoded protein is glutamine-rich due to CAG repeats in the coding sequence. A minor allele of this gene has been implicated in an elevated risk of breast cancer.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 1:25 (1x10e6 cells), Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

O15405

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 214-242 from the human protein was used as the immunogen for the TOX-3 antibody.

Clonality

Polyclonal

Isotype

Applications

FACS, WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the TOX-3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This TOX-3 antibody is available for research use only.

Storage Conditions

Aliquot the TOX-3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the TOX-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human MDA-MB453 lysate in the absence and presence of immunizing peptide, using TOX-3 antibody. Predicted molecular weight ~63 kDa.