AKR1B1 Antibody / Aldose reductase

AKR1B1 is a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. This protein catalyzes the reduction of a number of aldehydes, including the aldehyde form of glucose, and is thereby implicated in the development of diabetic complications by catalyzing the reduction of glucose to sorbitol.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Immunofluorescence: 1:25

UniProt

P15121

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 102-135 from the human protein was used as the immunogen for the AKR1B1 antibody.

Clonality

Polyclonal

Isotype

Applications

IHC-P, WB, IF

Purity

SAS precipitation

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the AKR1B1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This AKR1B1 antibody is available for research use only.

Storage Conditions

Aliquot the AKR1B1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the AKR1B1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.