Erythropoietin Receptor Antibody / EPOR

Receptor for erythropoietin. Mediates erythropoietin- induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)

UniProt

P19235

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 470-504 from the human protein was used as the immunogen for the Erythropoietin Receptor antibody.

Clonality

Polyclonal

Isotype

Applications

WB, FACS

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Erythropoietin Receptor antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Erythropoietin Receptor antibody is available for research use only.

Storage Conditions

Aliquot the Erythropoietin Receptor antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Erythropoietin Receptor antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) K562, 2) Jurkat, 3) HL60, 4) HepG2, 5) kidney and 6) placenta lysate with Erythropoietin Receptor antibody. Predicted molecular weight ~55 kDa.