STRADA Antibody / LYK5

Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Immunofluorescence: 1:25, Flow cytometry: 1:25 (1x10e6 cells)

UniProt

Q7RTN6

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 303-346 from the human protein was used as the immunogen for the STRADA antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, IF, FACS

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the STRADA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This STRADA antibody is available for research use only.

Storage Conditions

Aliquot the STRADA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the STRADA antibody may be required due to differences in protocols and secondary/substrate sensitivity.