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MSX1 Antibody

Homeobox protein MSX-1 is a member of the muscle segment homeobox gene family. The protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunofluorescence: 1:25

UniProt

P28360

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 111-138 from the human protein was used as the immunogen for the MSX1 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MSX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MSX1 antibody is available for research use only.

Storage Conditions

Aliquot the MSX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the MSX1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Nuclear

Image Legend

Western blot testing of mouse spleen lysate with MSX1 antibody. Predicted molecular weight ~31 kDa.

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