Bcl-W Antibody (BH3 domain specific)
Bcl-w is a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25
UniProt
Q92843
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 24-59 from the human protein was used as the immunogen for the Bcl-W antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
SAS precipitation
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Bcl-W antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Bcl-W antibody is available for research use only.
Storage Conditions
Aliquot the Bcl-W antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
Frequently Asked Questions
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