PREX1 Antibody
The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs) . It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
Q8TCU6
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 1134-1163 from the human protein was used as the immunogen for the PREX1 antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the PREX1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This PREX1 antibody is available for research use only.
Storage Conditions
Aliquot the PREX1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
IHC testing of FFPE human brain tissue with PREX1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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