Acid Sphingomyelinase Antibody / SMPD1
The protein encoded by this gene is a lysosomal acid sphingomyelinase that converts sphingomyelin to ceramide. The encoded protein also has phospholipase C activity. Defects in this gene are a cause of Niemann-Pick disease type A (NPA) and Niemann-Pick disease type B (NPB) . Multiple transcript variants encoding different isoforms have been identified. [provided by RefSeq].
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P17405
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 391-419 from the human protein was used as the immunogen for the Acid Sphingomyelinase antibody.
Clonality
Polyclonal
Isotype
IgG
Applications
IHC-P, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Acid Sphingomyelinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Acid Sphingomyelinase antibody is available for research use only.
Storage Conditions
Aliquot the Acid Sphingomyelinase antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
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