Sciellin Antibody / SCEL
The protein encoded by this gene is a precursor to the cornified envelope of terminally differentiated keratinocytes. This protein localizes to the periphery of cells and may function in the assembly or regulation of proteins in the cornified envelope. Transcript variants encoding different isoforms exist. A transcript variant utilizing an alternative polyA signal has been described in the literature, but its full-length nature has not been determined.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1:25, Western blot: 1:500-1:2000, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
O95171
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 260-289 from the human protein was used as the immunogen for the Sciellin antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
IHC-P, WB, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Sciellin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Sciellin antibody is available for research use only.
Storage Conditions
Aliquot the Sciellin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic, plasma membrane
Image Legend
IHC testing of FFPE human skin tissue with Sciellin antibody. HIER: steam section in pH9 EDTA for 20 min and allow to cool prior to staining.
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