Lingo1 Antibody
'Leucine-rich repeat and immunoglobulin domain-containing protein 1' is the functional component of the Nogo receptor signaling complex (RTN4R/NGFR) in RhoA activation responsible for some inhibition of axonal regeneration by myelin-associated factors. LINGO1 is also an important negative regulator of oligodentrocyte differentiation and axonal myelination. [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25
UniProt
Q9D1T0
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
A portion of amino acids 575-603 from the mouse protein was used as the immunogen for the Lingo1 Antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Lingo1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Lingo1 antibody is available for research use only.
Storage Conditions
Aliquot the Lingo1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Image Legend
IHC testing of FFPE human brain tissue with Lingo1 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.
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