BRD5459
BRD5459 is a ROS chemical probe. BRD5459 can increase ROS, a marker of oxidative stress in cells, without causing cell death[1].
Product Specifications
CAS Number
612037-58-8
UNSPSC
12352005
Target
ROS Kinase
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd5459.html
Smiles
N#CC1=C(C)C(CC=C)=C(NCCC2=CC=C(OC)C(OC)=C2)N3C4=CC=CC=C4N=C31
Molecular Formula
C26H26N4O2
Molecular Weight
426.51
References & Citations
[1]Adams DJ, et al. Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death. ACS Chem Biol. 2013 May 17;8 (5) :923-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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