BRD5459

BRD5459 is a ROS chemical probe. BRD5459 can increase ROS, a marker of oxidative stress in cells, without causing cell death[1].

Product Specifications

CAS Number

[612037-58-8]

UNSPSC

12352005

Target

ROS Kinase

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd5459.html

Smiles

N#CC1=C(C)C(CC=C)=C(NCCC2=CC=C(OC)C(OC)=C2)N3C4=CC=CC=C4N=C31

Molecular Formula

C26H26N4O2

Molecular Weight

426.51

References & Citations

[1]Adams DJ, et al. Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death. ACS Chem Biol. 2013 May 17;8 (5) :923-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

222788-01 50 µL

Frizzled-8 (Fz-8, hFz8, FZD8, FZ-8, Hfz8, Frizzled 8, Frizzled8) discontinued

Ask

View Details

222788-02 100 µL

Frizzled-8 (Fz-8, hFz8, FZD8, FZ-8, Hfz8, Frizzled 8, Frizzled8) discontinued

Ask

View Details

MBS6179632-01 0.1 mL

LEFTY1 (Left-right Determination Factor 1, LEFTB, LEFTYB) (HRP)

Ask

View Details

MBS6179632-02 5x 0.1 mL

LEFTY1 (Left-right Determination Factor 1, LEFTB, LEFTYB) (HRP)

Ask

View Details

AM31349AF-N 200 µg

ICAM2 Mouse Monoclonal Antibody [Clone ID: B-T1]

Ask

View Details

MBS9337742-01 48 Well

Rat Rod outer segment membrane protein 1, ROM1 ELISA Kit

Ask

View Details