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BRD5459

BRD5459 is a ROS chemical probe. BRD5459 can increase ROS, a marker of oxidative stress in cells, without causing cell death[1].

Product Specifications

CAS Number

612037-58-8

UNSPSC

12352005

Target

ROS Kinase

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/brd5459.html

Smiles

N#CC1=C(C)C(CC=C)=C(NCCC2=CC=C(OC)C(OC)=C2)N3C4=CC=CC=C4N=C31

Molecular Formula

C26H26N4O2

Molecular Weight

426.51

References & Citations

[1]Adams DJ, et al. Discovery of small-molecule enhancers of reactive oxygen species that are nontoxic or cause genotype-selective cell death. ACS Chem Biol. 2013 May 17;8 (5) :923-9.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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