LOX-1 Antibody / OLR1

OLR1 is a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

P78380

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 64-92 from the human protein was used as the immunogen for the LOX-1 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the LOX-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This LOX-1 antibody is available for research use only.

Storage Conditions

Aliquot the LOX-1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the LOX-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) A549, 2) HUVEC, 3) liver and 4) placenta lysate with LOX-1 antibody. Predicted molecular weight: pro-form 35-50 kDa, mature form ~31 kDa.