Hexosaminidase A Antibody / HEXA
HEXA is the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells)
UniProt
P06865
Host
Rabbit
Reactivity
Human
Immunogen
A portion of amino acids 142-170 from the human protein were used as the immunogen for the Hexosaminidase A antibody.
Clonality
Polyclonal
Isotype
Ig
Applications
WB, IHC-P, FACS
Purity
Antigen affinity purified
Format
Purified
Buffer
In 1X PBS, pH 7.4, with 0.09% sodium azide
Reconstitution
Aliquot the Hexosaminidase A antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Limitations
This Hexosaminidase A antibody is available for research use only.
Storage Conditions
Aliquot the Hexosaminidase A antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.
Formulation
In 1X PBS, pH 7.4, with 0.09% sodium azide
Applications Notes
Location
Cytoplasmic
Image Legend
IHC testing of FFPE human liver tissue with Hexosaminidase A antibody. HIER: steam section in pH9 EDTA for 20 min and allow to cool prior to staining.
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