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IDOL Antibody / MYLIP

The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Myosin regulatory light chain interacting protein (MYLIP), also called Inducible degrader of the LDL-receptor (IDOL), is a novel ERM-like protein that interacts with myosin regulatory light chain and inhibits neurite outgrowth.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Flow cytometry: 1:25 (1x10e6 cells)

UniProt

Q8WY64

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 111-139 from the human protein were used as the immunogen for the IDOL antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IHC-P, FACS

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the IDOL antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This IDOL antibody is available for research use only.

Storage Conditions

Aliquot the IDOL antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the IDOL antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) 293 and 2) MCF7 cell lysate with IDOL antibody. Predicted molecular weight ~50 kDa.

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