NGN3 Antibody / Neurogenin 3

Neurogenin-3 belongs to a family of basic helix-loop-helix transcription factors involved in the determination of neural precursor cells in the neuroectoderm. Neurogenin-3 also required for the specification of a common precursor of the 4 pancreatic endocrine cell types. Defects in NEUROG3 are the cause of congenital malabsorptive diarrhea 4 (DIAR4) . DIAR4 is an autosomal recessive disorder characterized by generalized malabsorption and a paucity of enteroendocrine cells.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25, Immunofluorescence: 1:25

UniProt

Q9Y4Z2

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 40-69 from the human protein were used as the immunogen for the NGN3 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P, IF

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NGN3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NGN3 antibody is available for research use only.

Storage Conditions

Aliquot the NGN3 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the NGN3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.