PSCA Antibody

PSCA is a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. It is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

O43653

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

A portion of amino acids 56-85 from the human protein were used as the immunogen for the PSCA antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PSCA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PSCA antibody is available for research use only.

Storage Conditions

Aliquot the PSCA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PSCA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of mouse 1) kidney, 2) stomach and 3) liver lysate with PSCA antibody. Expected molecular weight: 13-29 kDa depending on glycosylation level.