MCT4 Antibody / SLC16A3

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family-16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:500-1:2000, Immunohistochemistry (FFPE) : 1:25

UniProt

O15427

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

A portion of amino acids 433-462 from the human protein were used as the immunogen for the MCT4 antibody.

Clonality

Polyclonal

Isotype

Applications

WB, IHC-P

Purity

Antigen affinity purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the MCT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This MCT4 antibody is available for research use only.

Storage Conditions

Aliquot the MCT4 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the MCT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

IHC testing of FFPE human skeletal muscle tissue with MCT4 antibody. HIER: steam section in pH6 citrate buffer for 20 min and allow to cool prior to staining.