PD-L1 Antibody / C-Terminal Region

Programmed cell death 1 ligand 1 (PD-L1), also called CD274, is involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 1:1000

UniProt

Q9NZQ7

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 252-290 from the C-terminal region of the human protein was used as the immunogen for the PD-L1 antibody.

Clonality

Polyclonal

Isotype

Applications

Purity

Peptide affinity purified

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the PD-L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This PD-L1 antibody is available for research use only.

Storage Conditions

Aliquot the PD-L1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the PD-L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of 1) human heart and 2) human skeletal muscle lysate with PD-L1 antibody at 1:1000. Predicted molecular weight: 34-70 kDa depending on glycosylation level.