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Lubricin Antibody / PRG4 / N-Terminal Region

Proteoglycan 4 (PRG4), also called Lubricin, plays a role in boundary lubrication within articulating joints. Prevents protein deposition onto cartilage from synovial fluid by controlling adhesion-dependent synovial growth and inhibiting the adhesion of synovial cells to the cartilage surface.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 1:500, Immunofluorescence/Immunohistochemistry: 1:25

UniProt

Q92954

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 176-210 from the N-terminal region of the human protein was used as the immunogen for the Lubricin antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB, IF/ICC

Purity

Peptide affinity purified

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the Lubricin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This Lubricin antibody is available for research use only.

Storage Conditions

Aliquot the Lubricin antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the Lubricin antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Location

Cytoplasmic, secreted

Image Legend

Western blot testing of human liver lysate with Lubricin antibody at 1:500. Predicted molecular weight ~151 kDa.

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