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NKp30 Antibody / NCR3 / N-Terminal Region

Natural cytotoxicity triggering receptor 3 (NCR3), also called Natural killer cell p30-related protein (NKp30), is a cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western Blot: 1:1000

UniProt

O14931

Host

Rabbit

Reactivity

Human

Immunogen

A portion of amino acids 31-65 from the N-terminal region of the human protein was used as the immunogen for the NKp30 antibody.

Clonality

Polyclonal

Isotype

Ig

Applications

WB

Purity

Peptide affinity purified

Format

Antigen affinity purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the NKp30 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This NKp30 antibody is available for research use only.

Storage Conditions

Aliquot the NKp30 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the NKp30 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of human 1) Jurkat and 2) Daudi cell lysate with NKp30 antibody at 1:1000. Predicted molecular weight: 22-39 kDa depending on glycosylation level.

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