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SNCA Antibody / Alpha-Synuclein

Synuclein alpha (SNCA) may be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1:1000-1:2000

UniProt

P37840

Host

Mouse

Reactivity

Human, Mouse

Immunogen

Recombinant human SNCA protein was used as the immunogen for the SNCA antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Clone

1853CT506.24.16

Applications

WB

Purity

Protein G purified

Format

Purified

Buffer

In 1X PBS, pH 7.4, with 0.09% sodium azide

Reconstitution

Aliquot the SNCA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Limitations

This SNCA antibody is available for research use only.

Storage Conditions

Aliquot the SNCA antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Formulation

In 1X PBS, pH 7.4, with 0.09% sodium azide

Applications Notes

The stated application concentrations are suggested starting points. Titration of the SNCA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Image Legend

Western blot testing of 1) human brain and 2) mouse brain lysate with SNCA antibody at 1:2000. Predicted molecular weight ~15 kDa.

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